Corticosteroids alone rarely cause stomach ulcers. The real risk comes from combining them with NSAIDs. Learn who actually needs protective medication and how to monitor for dangerous signs without unnecessary drugs.
NSAIDs: What They Are, How They Work, and What You Need to Know
When you reach for NSAIDs, a class of pain relievers that reduce inflammation and fever. Also known as nonsteroidal anti-inflammatory drugs, they’re in almost every medicine cabinet — from ibuprofen to aspirin. But they’re not harmless. For some people, especially those with asthma, even a single pill can trigger a dangerous reaction.
NSAIDs work by blocking enzymes that cause pain and swelling, but that same action can upset the body’s natural balance. If you have asthma, you might be at risk for NERD, a condition where NSAIDs worsen breathing problems. Also known as aspirin-exacerbated respiratory disease, NERD affects up to 10% of adults with asthma and can cause wheezing, nasal congestion, or even full-blown attacks. It’s not just aspirin — ibuprofen and naproxen can do the same thing. Many people don’t realize they’re sensitive until they take one of these drugs after a headache or sore knee. And once you react, you’re likely to react again.
Not everyone needs to avoid NSAIDs. If you don’t have asthma or a history of bad reactions, they’re usually safe in small doses for short periods. But if you’re on blood thinners, have kidney issues, or take other meds like ACE inhibitors, NSAIDs can pile on risks. That’s why doctors warn against long-term use, even for something as simple as daily back pain. The same pills that help you move better might be quietly stressing your stomach, heart, or kidneys.
What you’ll find below are real stories and facts about how NSAIDs interact with other conditions — from asthma to kidney damage, from drug interactions to hidden dangers. You’ll learn who’s most at risk, what alternatives exist, and how to spot trouble before it turns serious. These aren’t just general warnings. They’re based on actual patient experiences and medical guidelines. If you’ve ever wondered why your doctor asked if you take ibuprofen, or why your breathing got worse after a painkiller, the answers are here.